The Effects of Coloprotectomy under Colonscopy Combined with Laparoscope on Exfoliated Tumor Cells in Abdominal Cavity
- VernacularTitle:结肠镜与腹腔镜联合切除结直肠癌对腹腔脱落肿瘤细胞的影响
- Author:
Yan LIU
;
Kai MIN
;
Zhao GONG
- Publication Type:Journal Article
- Keywords:
Laparoscope;
Colonoscopy;
Colorectal cancer;
Exfoliated tumor cells
- From:
Chinese Journal of Minimally Invasive Surgery
2005;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To stuey effects of coloprotectomy under colonoscopy combined with laparoscope on exfoliated tumor cells in abdominal cavity.Methods 42 cases of colorectal cancer proved by pathologic histology were devided into two groups randomly: Laparoscope Group(laparoscopic surgery) and Combined Group(colonoscopy combined with laparoscope surgery).Operation time,the positive rate of exfoliated tumor cells in abdominal cavity after and before operation,the positive rate of residual tumor cells in resection of operation specimen and postoperative complications between 2 groups were compared.Results Operation time of the Combined Group was shorter than that of the Laparoscope Group [(160.5?12.6) min vs.(201.2?18.4) min,t=-8.363,P=0.000].The positive rate of exfoliated cells in abdominal cavity before operation had no significant difference between the 2 groups[9.5%(2/21) vs.19.0%(4/21),?2=0.194,P=0.659],but the postoperative positive rate of exfoliated cells in the Combined Group was significantly lower than that in the Laparoscope Group[14.3%(3/21) vs.42.9%(9/21),?2=4.200,P=0.040].There were no residual tumor cells in resection of operation specimen of 2 groups.No infection of incisional wound and lung occurred.A follow-up for 6-24 months in the Laparoscope Group showed abdominal metastasis in 1 case.Conclusions Coloprotectomy for colorectal cancer under colonoscopy combined with laparoscope can decrease exfoliated tumor cells in abdominal cavity and shorten operation time.
