Risk Factors of Nosocomial Invasive Candidemia:Analysis and Prognosis of 59 Cases of Candidemia
- VernacularTitle:59例假丝酵母菌属菌血症的危险因素与预后分析
- Author:
Xinmao ZHAO
;
Yingchun XU
;
Xuesong YANG
;
Yang MA
;
Xiuli XIE
;
Minjun CHEN
- Publication Type:Journal Article
- Keywords:
Nosocomial candidemia;
Risk factors
- From:
Chinese Journal of Nosocomiology
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate predisposing factors of candidemia in nosocomial infections.METHODS To retrospectively review the clinical features of 120 cases,including 59 who developed candidemia and 61 cases with bacteremia during the period of 1990-2004.RESULTS The incidence of candidemia was stable over a 14-year period.Candida albicans remained the predominant Candida species recovered(30.5%),followed by C.tropicalis(25.7%),C.glabrata(12.9%),C.parapsilosis(12.9%) and others(17.1%).Of the total 59 cases of candidemia,were administrated by broad spectrum antibiotic therapy for long time,urinary catheters,malignant tumor,etc.Multivariate analysis showed that candidemia was related with many factors.CONCLUSIONS C.albicans was the major pathogen in our hospital during 14 years;the candidemia is related with the use of quinolones,ventilator,central venous catheters and radiation-chemotherapy(P
