Hijacking The Eukaryotic MAPK Pathway by Pathogens
- VernacularTitle:病原菌调节宿主细胞丝裂原活化蛋白激酶免疫防御信号的机理
- Author:
Jianning GE
;
Feng SHAO
- Publication Type:Journal Article
- Keywords:
mitogen-activated protein kinase(MAPK) ,innate immunity,pathogen
- From:
Progress in Biochemistry and Biophysics
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
MAPK(mitogen-activated protein kinase) family,which is conserved throughout high eukaryotes,is implicated in multiple cellular processes including cell growth,migration,proliferation,differentiation,survival and development.Pathogen hijacks hosts' MAPK pathways to facilitate its pathogenesis using diverse strategies.To further explore the mechanism underlying interactions between pathogens and hosts' MAPK pathway,is of benefit to our understanding of nature as well as to our fight against pathogen infection.
