Recognition of microRNAs and its-targeting genes
- VernacularTitle:miRNAs及其靶基因的识别
- Author:
Bao SONG
;
Xianrang SONG
;
Jie LIU
;
Ling WEI
- Publication Type:Journal Article
- Keywords:
microRNA s(miRNAs);
non-coding RNA;
target mRNA
- From:
Basic & Clinical Medicine
2006;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
microRNAs (miRNAs) are a recently discovered family of small non-coding RNAs, which exist in eukaryotes and regulate gene expression post-transcriptionally by binding to complementary sites on target mRNAs. MiRNAs play important roles in regulation of cell proliferation, development, apoptosis and cell differentiation. It’s predicted that about 1% human known genes encode microRNAs and microRNAs may regulate 10～30%of the genes in the human genome. The paper focus on the knowledge about how to recognize miRNAs and identify their target mRNAs.
