Comparison of atrial fibrillation inducibility due to electrical stimulation of the extrinsic vs the intrinsic cardiac autonomic innervation
- VernacularTitle:外源性与内源性自主神经刺激对心房颤动诱发性的影响
- Author:
Jing ZHOU
;
Yansheng DING
;
Yinglong HOU
- Publication Type:Journal Article
- Keywords:
Atrial fibrillation;
Autonomic pathways;
Vagus nerve
- From:
Chinese Journal of Interventional Cardiology
1996;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influence of cervical vagosympathetic trunk or ganglionated plexi stimulation to the inducibility of atrial fibrillation(AF) in dogs.Methods In 16 anesthetized dogs,right cervical vagosympathetic trunk(VST) were dissected.A right thoracotomy was used to expose fat pad(FP) containing the ganglionated plexi(GP) at the caudal end of the sinus node.An electrode catheter was attached along the right superior pulmonary vein to allow programmed atrial pacing.At 2?,4? and 10? threshold atrial refractory periods(ARPs) were determined with and without VST or GP stimulation.At each pacing threshold AF inducibility was measured from the window of vulnerability(WOV).A cumulative WOV sum made of all WOVs was calculated in each group.Results In the baseline state the heart rate(HR) averaged 153?22 beats/min.Slowing of the HR by VST stimulation(79?44 beats/min) was not significantly different than with GP induced slowing(87?99 beats/min,P=NS).Furthermore,there were no significant differences between the lowest ARPs with VST stimulation and GP stimulation,accounting to 90?17 ms and 91?13 ms respectively(P=NS),but both are shorter than that in the baseline state,which was 101?20 ms(P
