Fibrinolytic Dysfunction After A High-fat Meal Induced Postprandial Triglyceride and Inflammatory Responses in Normocholesterolemic Patients with Essential Hypertension
- VernacularTitle:餐后三酰甘油与炎症反应导致高血压患者高脂餐后纤溶功能紊乱
- Author:
Ling LIU
;
Shuiping ZHAO
;
Hongnian ZHOU
;
Min HU
;
Jixiang LI
- Publication Type:Journal Article
- Keywords:
High-fat meal;
Hypertension;
Inflammation;
Endothelium;
Fibrinolytic dysfunction
- From:
Chinese Journal of Hypertension
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the potential influence of a high-fat meal on systemic inflammation and fibrinolytic dysfunction in normocholesterolemic patients with essential hypertension(EH).Methods Plasma concentrations of lipids profiles,high-sensitivity C-reactive protein(hsCRP),plasminogen activator inhibitor type 1(PAI-1)and tissue plasminogen activator(t-PA)antigens in fasting state(F)and at 4 hours after a single high-fat meal(P)were measured in 54 EH patients and 30 healthy controls(Con).Results Postprandial triglyceride concentrations increased significantly in both hypertensive patients and healthy controls(P
