Value of differential diagnosis of 5-hydroxytryptamine,dopamine and their metabolic productions in cerebral spinal fluid in patients with viral encephalitis and schizophrenia
- VernacularTitle:脑脊液5-羟色胺和多巴胺及其代谢产物在病毒性脑炎和精神分裂症鉴别诊断中的价值
- Author:
Chunyu WANG
;
Liming TAN
;
Bo JIANG
- Publication Type:Journal Article
- Keywords:
viral encephalitis;
schizophrenia;
5-hydroxytryptamine;
dopamine;
high-performance liquid chromatography
- From:
Journal of Clinical Neurology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of differential diagnosis of 5-hydroxytryptamine,dopamine and their metabolic productions in cerebral spinal fluid(CSF) in patients with viral encephalitis and schizophrenia.Methods The CSF concentrations of DA,5-HT,5-hydroxyindole acetic acid(5-HIAA) and homovanillic acid(HVA) were assayed by high-performance liquid chromatography(HPLC) in the patients with viral encephalitis and meningoencephalitis(67 cases),schizophrenia(37 cases) and other diseases(21 cases).Results(1) Compared with case control group,the concentrations of 5-HT,5-HIAA and the ratios of 5-HIAA/5-HT,5-HT/DA were significantly lower in viral encephalitis and meningoencephalitis group(P
