Clinical characteristics and diagnosis of general paresis of insane (report of 2 cases)
- VernacularTitle:麻痹性痴呆的临床特征与诊断(附2例报告)
- Author:
Biao JIN
;
Kangren ZHAO
;
Weifang ZHANG
- Publication Type:Journal Article
- Keywords:
neurosyphilis;
general paresis of insane;
clinical characteristic;
diagnosis
- From:
Journal of Clinical Neurology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characteristics of general paresis of insane(GPI) and diagnostic value of laboratory and neuroimaging examinations.Methods The clinical data of 2 patients with GPI were analyzed retrospectively and the pertinent literatures were reviewed.Results The main clinical characteristics consisted of insidious onset,progressive dementia,mental disorder and epileptic seizure.These 2 patients were originally misdiagnosed.Both rapid plasma reagin test and treponema gelatin agglutination test in serum and cerebrospinal fluid were positive.Cranial MRI showed diffuse cerebral atrophy.Conclusions The clinical characteristics of GPI are varied and misdiagnosis rate is high at early stage of this disease.The diagnosis of GPI mainly depends on clinical characteristics,serum and cerebrospinal fluid examinations.
