Statins-associated myopathy (analysis of 5 cases)
- VernacularTitle:他汀类药物致肌病(附5例分析)
- Author:
Qian SU
- Publication Type:Journal Article
- Keywords:
statins;
myopathy
- From:
Journal of Clinical Neurology
1995;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical changes,alterations of electromyography(EMG) and serum-correlated enzyme in statins-associated myopathy.Methods The clinical trait,alterations of EMG and creatases were analyzed in 5 patients with statins-associated myopathy.Results The average age of 5 patients was 60 years old.They took statins from 2 weeks to 2 years and 2 cases of them also took other medicines.4 patiens felt general pain or pain of inferior extremities.3 patients felt limb hypodynamia and 2 patients had mild muscle weakness.3 patients had muscle haphalgesia.The values of creatine kinase in all the cases were increased to different degree.EMG examination was performed in 2 patients.The result of 1 case was normal and the other case was myogenic change.The symptoms of myopathy were nearly recoverd after withdrawal for 2～3 weeks.Conclusions The statins-associated myopathy is not rare in clinic.Old patients or the patients with other foundational diseases have more chance to suffer this disease.But the prognosis is good after in time withdrawal of statins.
