The Changes of Main Oxidase and Antioxidase Activities in The Pathological Scars
- VernacularTitle:病理性瘢痕中主要氧化酶和抗氧化酶活性测定
- Author:
Weiren LI
;
Ying CEN
;
Xiaoxue LIU
;
Xiaohong LI
;
Fengqiong ZUO
- Publication Type:Journal Article
- Keywords:
hypertrophic scars,keloids,xanthine oxidase,antioxidase,malonaldehyde
- From:
Progress in Biochemistry and Biophysics
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
In order to study the changes of main oxidase and antioxidase in the pathological scars,the tissues of hypertrophic scar(10 cases),keloid(10 cases)and normal skin(8 cases)were obtained.The concentration of malonaldehyde(MDA)and the activities of xanthine oxidase(XO),copper,zinc-superoxide dismutase(CuZn-SOD),catalase(CAT)as well as glutathione peroxidase(GPX)were detected by spectrophotometric method.Compared with normal skin tissues,the concentration of malonaldehyde and xanthine oxidase activity were significantly higer in pathological scars(P