Progress in transplantation of differentiated embryonic stem cells for treatment of Parkinson disease
- VernacularTitle:胚胎干细胞移植治疗帕金森病的研究进展
- Author:
Jing WANG
;
Yali LI
;
Hongmei PENG
- Publication Type:Journal Article
- Keywords:
Parkinson disease (PD);
embryonic stem cell (ESC);
dopaminergic neurons;
transplantation
- From:
Basic & Clinical Medicine
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson disease(PD) is a degenerative disorder characterized by the loss of midbrain dopamine (DA) neurons. Recently it has been demonstrated that ES cells can differentiate into dopaminergic neurons in vitro and is a potentiol item for transplantation. In this paper we reviewed clinical study in treating Parkinson disease、methods and mechanisms of ES cells differentiation into dopaminergic neurons in vitro and progress of its application.
