Alteration of Serum Soluble Vascular Endothelial Growth Factor Receptor-1 in Pregnancy Complicated with Eclampsia
- VernacularTitle:子痫时可溶性血管内皮生长因子受体1的变化
- Author:
Lihong CHEN
;
Yun LI
;
Jifen HU
- Publication Type:Journal Article
- Keywords:
Eclampsia;
Pre-eclampsia;
Soluble vascular endothelial growth factor receptor-1;
Vascular endothelial growth factor
- From:
Chinese Journal of Hypertension
2007;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the level of serum vascular endothelial growth factor and soluble vascular endothelial growth factor receptor-1 in patients with pre-eclampsia and eclampsia.Methods Serum vascular endothelial growth factor and soluble vascular endothelial growth factor receptor-1 in peripheral venous blood were determined by ELISA in patients with pre-eclampsia(n=9),severe pre-eclampsia(n=10) and eclampsia(n=5)(total eclampsia n=24) and healthy controls(n=18).Results Patients with pre-eclampsia and eclampsia had higher level of serum sVEGFR-1(pre-eclampsia:58?7 mg/L,severe pre-eclampsia:82?15 mg/L,eclampsia:96?13 mg/L vs control:11?3 mg/L,P