Protecting effects of topical hypothermia to blood-ocular barriers in intraocular operation
- VernacularTitle:内眼手术中局部低温对血-眼屏障的保护作用
- Author:
Jun LIU
;
Yizhuang LI
;
Hui CHEN
;
Honglin YIN
- Publication Type:Journal Article
- Keywords:
Topical hypothermia;
Intraocular operation;
Blood-ocular barrier;
Intraocular irrigating solution;
Retina;
Vitrectomy
- From:
Journal of Medical Postgraduates
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate whether topical hypothermia circumstance has the protective effects to the blood-ocular barriers during intraocular operations.Methods:Twenty New Zealand albino rabbits accepted vitrectomy in both eyes,useing hypothermal(4-10℃) intraocular irrigating solution in left eye(hypothermal intraocular irrigating solution group),and useing room temperature(25℃) intraocular irrigating solution in right eye(room temperature intraocular irrigating solution group)during the vitrectomy.Twenty-four hours after the operation,the retina of both eyes were checked;each eye accepted cavum vitreum perforation,and 0.5 ml of intraocular fluid were aspirsted for biochemical detection as well;as well as the retinas cut off for transmission electron microscopical(TEM) observations. Results:Inflammatory reaction of anterior ocular and the uvea in left eyes were generally slighter than the right eyes;dioptric media clarity of left eyes were also better than that in left eyes;average total protein concentration of the intraocular fluid was obviously lower than that in left eye(P
