Advances in the study on association of Wnt-5a with tumor
- VernacularTitle:Wnt-5a与肿瘤的研究进展
- Author:
Xiaohong LIU
;
Xiaojun ZHOU
- Publication Type:Journal Article
- Keywords:
Wnt;
Wnt-5a;
Signal transduction;
Vtumor
- From:
Journal of Medical Postgraduates
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Wnt gene family has been shown to encode the multifunctional signaling glycoproteins that are involved in the regulation of a wide variety of normal and pathologic processes,including embriogenesis,differentiation,and tumorigenesis.Recent studies have demonstrated that the Wnt-5a expression is frequently deregulated in various human cancers,which suggested that Wnt5a shuld be a good marker for progression and prognosis of tumor,but the role of Wnt-5a is controversial in different tumors.Here,we assemble evidence of possible relations between Wnt and various tumors.