Genetic polymorphisms of six STR loci in Maonan population in Guangxi province
- VernacularTitle:广西毛南族6个短串联重复序列的遗传多态性
- Author:
Shaokang TENG
;
Lin XU
;
Ming LAO
;
Lining ZHOU
;
Qiongying DENG
;
Songfeng LI
;
Jichun GONG
- Publication Type:Journal Article
- Keywords:
short tandem repeats;
genetic polymorphisms;
Maonan Ethnic group;
phylogenetic analysis
- From:
Basic & Clinical Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution of six short tandem repeats(STR) loci in Maonan in Guangxi province and to study genetic relationship among 6 minorities.Methods Two hundreds unrealated individulas were analyed by STR genescanning.Genetic distance was computed and phylogenetic tree was construted for studying genetic relationship among 6 Ethnic groups.Results The average heterozygosity(H) in the six STR loci was 0.7825;the average polymorphism information content(PIC) was 0.7324;the accumulative discrimination power(DP) was 0.99999951,and the accumulative probability of paternity exclusion(EP) was 0.994575.All 6 populations were clustered into 2 group.Conclusion Allele 16 in D3S1358,allele 11 in D5S818,allele 11 in D7S820,8 in D13S317,14 in vWA,22 in FGA are probably the most primitive alleles in repective locus.The data obtained indicate highly genetic polymorphisms.Genetic relation between Maonan and Mulao were close.
