Clinical significance of thyroid peroxidase antibody level in the diagnosis and treatment of hyperthyroidism and thyroid gland tumor
- VernacularTitle:甲状腺过氧化物酶抗体在甲亢、甲状腺占位性病变诊治中的临床意义
- Author:
Yuguo ZHANG
;
Yunong WANG
- Publication Type:Journal Article
- Keywords:
hyperthyroidism,thyroid gland tumor,thyroid peroxidase antibody(TPOAb),hypothyroidis
- From:
Basic & Clinical Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the change of serum thyroid peroxidase antibody(TPOAb) in the patients with Hyperthyroidism and Thyroid gland tumor of different phases.Methods The level of TPOAb was observed,the relation between the changed TPOAb level and reduced thyroid function was studied.Results Among 89 cases,50 cases had normal or slightly elevated TPOAb level.However,after treatment,31 cases showed a raised TPOAb level.Of 19 cases with hypothyroidism or its sub-clinical type.There were 39 cases with positive TPOAb.After the treatment,2 cases changed to negative TPOAb,26 cases lowered,and 3 cases had hypothyroidism.There were 29 cases taking thyroid tablets without hypothyroidism.Conclusion The change of TPOAb level can be observed during the treatment for hyperthyroidism and t hyroid gland tumor.The elevated TPOAb level often predicts the decreased thyroid function.The patients with positive TPOAb should be carefully followed,and for hyperthyroidism patients the treatment should be taken with care.
