Negtive correlation between mast cell area ratio and the atypical degree of neoplasm from uterine smooth muscles
- VernacularTitle:子宫肿瘤恶性程度与肥大细胞脱颗粒后面积呈负相关
- Author:
Deyuan GUAN
;
Shaoxin WU
;
Jingfang ZHANG
;
Wenli HUANG
;
Xin CHEN
;
Dong XIA
;
Deji CHEN
- Publication Type:Journal Article
- Keywords:
uterus;
neoplasm;
mast cell
- From:
Basic & Clinical Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of infiltrated mast cells on the biological characteristics of uterine carcinoma.Methods Twelve leiomyomas,ten uncertain malignant uterine leiomyomas,and seven uterine leiomyosarcomas were studied with light microscopy for the morphometry about their histological feature,mast cell particle and factor Ⅷ-related antigen(FⅧRAg);Cell apoptosis was measured by flow cytometry.The correlative analysis was carried out between the mast cell and others factors.Results Comparing with smooth muscle tumors of uncertain malignant potential(4209.9?273.0),the count of tumor cell was the highest in leiomyosarcoma(3557.6?346.3)(P
