Genetic susceptibility study on hepatitis B
- VernacularTitle:乙型肝炎遗传易感性研究
- Author:
Li WANG
;
Hui LI
- Publication Type:Journal Article
- Keywords:
hepatitis B;
genetic susceptibility;
association study
- From:
Basic & Clinical Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B virus infection can result in different clinical outcomes which consist of self-limited infection(virus clearance),asymtomatic carrier status,chronic hepatitis B and cirrhosis.The mechanism led to individual discrepancy for outcome of hepatitis B virus infection is unknown yet.It is suspected that the outcomes of hepatitis B virus infection might be associated with the inherent factors of host.The results of association studies between genetic polymorphisms of HLA-I,Ⅱ class,TNF-? and VDR and different clinical outcome of hepatitis B virus infection in recent years are reviewed.
