Study on coagulant state in deep vein thrombosis patients with low level of coagulant factor Ⅻ
- VernacularTitle:凝血因子Ⅻ活性降低的深静脉血栓患者凝血状态初步探讨
- Author:
Yumin WANG
;
Jie CHEN
- Publication Type:Journal Article
- Keywords:
coagulant factor Ⅻ;
deep veins thrombosis;
coagulant state
- From:
Chinese Journal of Clinical Laboratory Science
1985;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Ojective To study the coagulant state in the patients with deep vein thrombosis(DVT)caused by low level of coagulant factor Ⅻ.Methods Blood samples were obtained from 125 patients with deep veins thrombosis and 32 normal people(control group).Before thrombolysis the following parameters were tested:thrombolysis Ⅻ:C coagulant activity(FⅫ:C),prothrombin time(PT),activated prothrombin time(APTT),thrombin time(TT),fibrinogen(FIB),antithrombin activity(AT:A),D-dimer(D-D),plasminogen activity(PLG:A),lupus anticoagulant(LAC),protein C(PC),tissue plasminogen activator antigen(t-PA:Ag),plasminogen activator inhibitor-1 antigen(PAI:Ag).According to the activity of FⅫ:C,the patients were divided into 2 groups:normal Ⅻ:C group and low FⅫ:C group.Results The PLG:A,PC,AT:A,t-PA:Ag in the low FⅫ:C group was lower evidently than those in normal group(P0.05).Compared to the FⅫ:C normal group,t-PA:Ag in the low FⅫ:C group decreased(P
