Effect of unfractioned heparin and low molecular weight heparin on expression of plasma hepatocyte growth factor in patients with unstable angina pectoris who undergo percutaneous coronary intervention
- VernacularTitle:经皮冠状动脉介入治疗患者应用普通肝素和低分子肝素对血浆肝细胞生长因子水平的影响
- Author:
Guoxin TONG
;
Ningfu WANG
;
Xingwei ZHANG
- Publication Type:Journal Article
- Keywords:
Coronary artery disease;
Hepatocyte growth factor;
Angioplasty,transluminal,percutaneous coronary;
Heparin
- From:
Chinese Journal of Interventional Cardiology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of unfractioned heparin and low molecular weight heparin on expression of plasma hepatocyte growth factor(HGF)during percutaneous coronary intervention(PCI).Methods Seventy four patients with unstable angina pectoris were classfied into unfractioned heparin(UFH)group(n=49)and low molecular weight heparin(LMWH)group(n=25)according to the type of heparin used during PCI.The plasma levels of HGF were measured before,during,and after PCI in the patients.Results The plasma levels of HGF before procedure were of no statistical difference between the two groups.The levels of HGF were significantly increased during and after PCI in the unfractioned heparin and the LMWH group.Comparing with the pre-procedure level,the post-procedure level of HGF in the UFH group was 13 565.60?3 768.99 ng/L(vs 1 736.09?603.95 ng/L,P
