Study the relationship between the serum paraoxonase-1 activity and its gene polymorphism and atherosclerotic thrombotic cerebral infarction
- VernacularTitle:血清对氧磷酯酶-1活性及其基因多态性与动脉粥样硬化性血栓性脑梗死关系的研究
- Author:
Yun SONG
;
Guiling TIAN
;
Tongyu WANG
- Publication Type:Journal Article
- Keywords:
paraoxonase-1;
cerebral infarction;
gene polymorphism
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the serum paraoxonase-1(PON1) activity, PON1Q/R192 polymorphism and atherosclerotic thrombotic cerebral infarction(ATCI) in Chinese Han people.Methods In 48 cases with ATCI and 55 normal controls (NC group), serum PON1 activity was assayed by infrared spectrophotometer;the PON1Q/R192 polymorphism was determined by polymerase chain reaction and restriction fragment length polymorphism.Results Serum PON1 acuivity in the ATCI group was significantly lower than that in NC group[(74.41?18.85) U/ml,(113.65?26.64) U/ml, P
