Study the expressions of apoptotic modulating genes of peripheral blood monocytes in patients with myasthenia gravis
- VernacularTitle:重症肌无力患者外周血单核细胞凋亡调控基因表达的研究
- Author:
Shimeng ZHANG
;
Min LIU
;
Chen ZHANG
- Publication Type:Journal Article
- Keywords:
myasthenia gravis;
apoptosis;
Fas
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the expressions and significances of apoptotic modulating genes Fas and Bcl-2 mRNA in peripheral blood monocytes(PBMC)of patients with myasthenia gravis (MG). Methods The levels of Fas and Bcl-2 mRNA in PBMC were detected by semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) in 44 patients with MG as well as 30 healthy donors served as a normal control (NC).Results (1) The level of Fas mRNA in MG group was no significantly difference compared with NC group. The level of Bcl-2 mRNA in MG group was higher than that in NC group(P
