Clinical analysis of 59 cases of meningeal careinomatosis
- VernacularTitle:脑膜癌病59例临床分析
- Author:
Qi SUN
;
Li WANG
;
Zhenliu ZHANG
- Publication Type:Journal Article
- Keywords:
meningeal carcinomatosis;
cerebrospinal fluid;
cytology
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss clinical and cytological features of cerebrospinal fluid (CSF) in meningeal careinomatosis (MC). Methods The data of clinic, imaging and CSF of 59 inpatients with MC were analyzed retrospectively. Results There were 91.5% (54 cases) of middle and elder aged in the group. Most of patients were at acute or subacute onset . Condition developed fast. 55 cases (93.2%) didn't feel fever primarily. Intracranial hypertension of headache (57 cases ),vomitted(45 cases ) and disc edema(21 cases ) ect. were predominant features. In 32 cases (54.2%), cranial nerves were involved. Optic never and abducent never damage appeared the most frequently. Oculomotor never, facial nerve and vestibulocochlear nerve were in the next. All of 59 cases had meningeal irritation sign, among them 31 cases (52.5%) with obvious sign. Tumor cells in cytological examination of CSF were found in all of 59 cases. Conclusions The clinical manifestations of MC has some certain features. Diagnosis of MC still relay on finding tumor cells in cytological examination of CSF.