Study on protective mechanism of Fleabane on PC12 cells impaired by hypoxia-reoxygention
- VernacularTitle:灯盏细辛对缺氧复氧损伤的PC12细胞保护机制的研究
- Author:
Qidi ZHOU
;
Wenqiong YANG
- Publication Type:Journal Article
- Keywords:
Fleabane;
PC12 cells;
hypoxia-reoxygention;
Bcl-2;
Bax
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protective effective mechanism of Fleabane on PC12 cells impaired by hypoxia-reoxygention (HR).Methods The PC12 cells cutured in vitro were grouped as following:normal control (NC) group, the HR group,Fleabane 10?mol/L (E1)group, 20?mol/L (E2)group, 30?mol/L (E3)group. The livability of PC12 was measured after impaired by HR in groups HR and E1～E3. The expressions of Bcl-2 and Bax were also detected by Western Blot. Results (1)Compared with NC group,the survival rate of PC12 decreased in HR group(P
