Peroxisome proliferator-activated receptors and acute lung injury
- VernacularTitle:过氧化物酶增殖物激活受体与急性肺损伤
- Author:
Fang FANG
;
Jianchun WANG
- Publication Type:Journal Article
- Keywords:
Peroxisome proliferator-activated receptors;
Acute lung injury;
Inflammation
- From:
Journal of Medical Postgraduates
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Peroxisome proliferator-activated receptors(PPAR) are ligand-activated nuclear transcription factors which regulate the expression of many genes.Numbers of researchs indicate PPAR exert anti-inflammatory activities by inhibiting the expression of inflammatory singal transcription passage such as NF-?B,AP-1,STAT,meanwhile preserve from acute lung injury.This review will focus on structure of PPAR and their ligand and activity regulation and antiinflammation mechanism of action and protection to acute lung injury.
