Role of Wnt signaling pathway in hepatocellular carcinoma
- VernacularTitle:WNT信号转导在肝细胞癌发病中的作用
- Author:
Long WU
;
Yeben QIAN
- Publication Type:Journal Article
- Keywords:
Wnt signaling pathways;
Hepatocellular carcinoma;
Angiogenesis;
Invasion;
Metabasis
- From:
Journal of Medical Postgraduates
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Wnt proteins,its receptors and regulators compose complex signaling pathways which are closely related to embryonic development,cell proliferation and differentiation,as well as tumour generation.In recent years,the involvement of Wnt signaling pathways in hepatocarcinogenesis has drawn the attention of international medical circles and been studied intensively.In this review,we summaries the interaction between Wnt signaling pathways and its regulators,the relationship between Wnt signaling pathways and cancerogenesis,angiogenesis,invasion and metabasis in hepatocellular carcinoma.