Progress in Aptazymes
- VernacularTitle:适体酶Aptazymes的研究进展
- Author:
Yanli ZENG
;
Xiaopeng LAN
- Publication Type:Journal Article
- Keywords:
aptazymes, allosteric ribozymes, allosteric deoxyribozymes, allosteric selection, catalytic molecular beacon, AND gate
- From:
Progress in Biochemistry and Biophysics
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Aptazymes are a new artificial synzyme, selected from the random oligonucleotide sequence libraries against various of effector molecules. They own the advantages of an aptamer(the receptor site) and the ribozyme (the catalytic active site). Moreover, aptazymes as catalytic molecular beacon provide a new orientation for the quantitative analysis of effector molecules. Aptazymes not only have the application in genomics and proteomics, but also have potential applications in biosensor and DNA AND gate.
