Relationship of Interleukin-8 and Granulocyte-colony Stimulating Factor with Helicobacter pylori Infection in Gastric Mucosa
- VernacularTitle:IL-8和粒细胞集落刺激因子与幽门螺杆菌感染的关系
- Author:
Weibing YIN
;
Lili CAI
;
Chunjin XU
;
Junling ZHAO
- Publication Type:Journal Article
- Keywords:
Helicobacter pylori;
Enzyme linked immunosorbent assay;
Interleukin-8;
Granulocyte-colony stimulating factor
- From:
Chinese Journal of Nosocomiology
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the relationship between the amount of interleukin-8(IL-8) and granulocyte colony-stimulating factor(G-CSF) and Helicobacter pylori(Hp) infection in gastric mucosa.METHODS Enzyme linked immunosorbent assay(ELISA) was used to detect the amount of IL-8 and G-CSF in 56 patients including normal gastric mucosa(n=18) and H.pylori infection patients(n=38) who were performed with gastroscope with their supernate fluid of gastrostoma mucosa tissue culture,and to examine the difference between Hp infected cases and non-Hp infected ones and H.pylori infection patients before and after treatment.RESULTS The amount of IL-8 and GCSF in Hp infected cases was significantly higher than non-infected ones(P
