ESBLs-producing Escherichia coli and Klebsiella pneumoniae and Their Antibiotic Resistance Changing
- VernacularTitle:大肠埃希菌与肺炎克雷伯菌产ESBLs及耐药性变迁
- Author:
Yongxiang LI
;
Xiulan SONG
;
Shuguang DING
;
Lixia ZHANG
- Publication Type:Journal Article
- Keywords:
Escherichia coli;
Klebsiella pneumoniae;
Extended-spectrum ?-lactamases(ESBLs);
Antibiotic resistance
- From:
Chinese Journal of Nosocomiology
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate ESBLs-producing Escherichia coli and Klebsiella pneumoniae and their antibiotic resistance changing at the same area in different period.METHODS Using Bio-Merieux ATB susceptibility test panels microdilution broth method to detect the antibiotic resistance of E.coli and K.pneumoniae,in addition to the use of phenotypic confirmatory test to detect the ESBLs.RESULTS The ESBLs-producing rate of E.coli and K.pneumoniae during 1999-2001 compared with 2003-2005,was elevated more than double.To imipenem,cefoxitin,piperacillin/tazobactam,and amikacin,the resistant rate was relatively lower,but to other ?-lactams,aminoglycosides,quinolones and sulfonamides,the resistant rate increased significantly in both periods compared,the differences were significant(P
