Relationship between therapeutic effects of ~(89)SrCl_2 on osteodynia induced by multiple bone metastases and ET,CGRP,TXB_2 and 6-K-PGF_(1a)
- VernacularTitle:~(89)SrCl_2治疗多发性骨转移癌骨痛与ET、CGRP、TXB_2、6-K-PGF_(1a)的关系
- Author:
Wenwei SUN
;
Liqin WEI
;
Ping TAN
;
Qingjie MA
- Publication Type:Journal Article
- Keywords:
89SrCl2;
multiple bone metastasis;
ET;
CGRP;
TXA2;
6-K-PGF1a
- From:
Journal of Jilin University(Medicine Edition)
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between therapeutic effects of 89SrCl2 on osteodynia induced by multiple bone metastasis and ET,CGRP,TXB2 and 6-K-PGF1a.Methods 89SrCl2 treatment was used in 39 cases of multiple bone metastasis,the serum content of ET,CGRP,TXB2 and 6-K-PGF1a were detected with radioimmunological method pre-treatment and 1,3,6 months post-treatment,respectively;the ET/CGRP value was calculated.Results The content of ET showed no obvious changes 1 month post-treatment compared with pre-treatment.However,the ET contents increased significantly 3 and 6 months post-treatment compared with 1 month post-treatment and before treatment(P
