Progress of Caveolin and Its Role in Brain
- VernacularTitle:Caveolin与脑功能关系的研究进展
- Author:
Lu WANG
;
Zhihong JI
;
Dongdong CHEN
;
Hongxia WANG
;
Wei ZOU
- Publication Type:Journal Article
- Keywords:
Caveolin,neural development,synaptic plasticity,neurodegenerative diseases
- From:
Progress in Biochemistry and Biophysics
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Caveolins are a family of plasmalemmal vesicles caveolae-associated integral membrane proteins and a marker protein of caveolae involved in the formation and localization that associated with vesicular transport, cellular cholesterol homeostasis and signal transduction. Recent years, strong experimental evidences indicated that caveolins play a pivotal role in the brain function such as neural development, synaptic plasticity and neurodegenerative diseases. Recent progress on studies of the structure and functions of caveolins was simply summarized. The regulatory role of caveolins in the brain functions has been reviewed and expected.
