Changes in Serum Levels of TNF-? and IL-6 and Relationship with Multiple Organ Dysfunction Syndrome after Thoracic Operation
- VernacularTitle:高危患者术后TNF-?及IL-6水平变化与感染性并发症及MODS关系的研究
- Author:
Zhiyong HUANG
;
Jun ZHANG
- Publication Type:Journal Article
- Keywords:
Operation;
Tumor necrosis factor-?;
Interleukin-6;
Mulitple organ dysfunction syndrome
- From:
Chinese Journal of Nosocomiology
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the changes in serum levels of TNF-? and IL-6 after thoracic operation,and the relationship with multiple organ dysfunction syndrome(MODS).METHODS Serum levels of TNF-? and IL-6 in 46 cases of benign disease between 2000 to 2003 were observed on the day of operation,the 3rd,7th,14th and 21th days after operation,the patients were divided into two groups according to the presence of MODS.RESULTS Cases occurred MODS in two weeks after thoracic operation,the serum levels of TNF-? and IL-6 were markedly higher in MODS than that in non-MODS,the correlation coefficients between them were r=0.9145,P