Effects of Polysaccharide Sulfate on plasma von Willebrand factor and thrombomodulin in patients with acute cerebral infarction
- VernacularTitle:藻酸双酯钠对急性脑梗死患者血浆血管性假血友病因子和血栓调节蛋白的影响
- Author:
Yongjiu WANG
;
Kun LIU
;
Shiqiang BI
- Publication Type:Journal Article
- Keywords:
von Willebrand factor;
thrombomodulin;
acute cerebral infarction;
Polysaccharide Sulfate
- From:
Journal of Clinical Neurology
1988;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of Polysaccharide Sulfate (PSS) on plasma von Willebrand factor (vWF) and thrombomodulin (TM) in patients with acute cerebral infarction.Methods 64 patients with acute cerebral infarction were randomly assigned to receive intravenous drip of PSS (150 mg/d for 14 days, 32 cases, PSS group) or Troxerutin (600 mg/d for 14 days, 32 cases, control group). All of the patients were tested for plasmatic levels of vWF and TM prior to and at 7 d, 14 d after treatment.Results The levels of vWF in PSS group at 7 d, 14 d after treatment were obviously decreased compared with control group (all P