Changes and correlation between nuclear factor-?B expression and water content in cerebral tissue after experimental intracerebral hemorrhage
- VernacularTitle:实验性脑出血后脑组织核因子-?B表达和含水量的变化及其相关性
- Author:
Jiami WU
;
Xiangyang ZHOU
;
Zaohu CHU
- Publication Type:Journal Article
- Keywords:
intracerebral hemorrhage;
nuclear factor-?B;
brain water content
- From:
Journal of Clinical Neurology
1988;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes and correlation between nuclear factor-?B (NF-?B) expression and brain water content (BWC) in perihematoma after experimental intracerebral hemorrhage (ICH) in rats. Methods Experimental ICH models of rat were made by injecting autologous blood using stereotaxic method. The expression of NF-?B in cerebral tissues was detected by immunohistochemistry technique. At the due time, BWC was measurement by day-wet method.Results NF-?B expression increased obviously at 6 h and peaked at 48 h in ICH group(P