Study on the free radical scavenging activities and structurefunction relationships of glycoprotein from jellyfish (R.e) oralarms
- VernacularTitle:海蜇头糖蛋白清除自由基活性及构效关系的初步研究
- Author:
Guoyan REN
- Publication Type:Journal Article
- Keywords:
Jellyfish oral-arms;
glycoprotein;
free radicals;
structure-function relationships
- From:
Chinese Journal of Marine Drugs
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the free radical scavenging activities and structure-function rela- tionship of glycoprotein(JF-Ⅲ)from jellyfish(R.e)oral-arms.Methods The scavenging ac- tivities on superoxide and hydroxyl radicals were estimated by chemiluminescence method, and the structure-function relationships were initial studied by chemical and enzymatic hy- drolysis methods.Results The free radical scavenging activities of the glycoprotein had sig- nificant dose-dependent relationship.The carbohydrate moiety and the protein moiety were both involved in scavenging activities on free radicals.N-linked sugar of JF-Ⅲplayed major roles in free radical scavenging activities,but O-linked sugar played minor roles.Conclusion JF-Ⅲhad strong free radical scavenging activities,which had close relations with its struc-ture.
