Detection of HLA-G and establishment of prognostic indicator for preeclampsia
- VernacularTitle:HLA-G检测及先兆子痫产前预诊指标建立
- Author:
Xinliua SUN
;
Xiulanb LIU
- Publication Type:Journal Article
- Keywords:
HLA-G;
preeclampsia;
prognostic indicator
- From:
Chinese Journal of Clinical Laboratory Science
1985;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To pre-diagnose and pre-group preeclamsia by detecting soluble HLA-G(sHLA-G) in serum of pregnant women.Methods Serum sHLA-G was detected with enzyme-linked immunosorbent assay(ELISA) and placental HLA-G was detected for retrospective research by RT-PCR.Results Serum and placental HLA-G decreased significantly in the preeclampsia group compared with normal pregnant females.The levels of sHLA-G in serum were significantly different between the two groups.Conclusion Serum sHLA-G can be measured as a prognostic indictor for the pregnant females who may be potential preeclampsia patients of special types.
