Clinical research of malignant hydrothorax or hydroperitoneum treated with intracavitary chemotherapy and local endogenetic thermotherapy
- VernacularTitle:内生场热疗联合腔内化疗治疗恶性胸腹腔积液的临床研究
- Author:
Haizhu SONG
;
Jiansheng QI
;
Jinghua WANG
;
Qun ZHANG
;
Xiaoyuan CHU
;
Huaicheng GENG
;
Xiaoxiang GUAN
;
Jie JIN
;
Longbang CHEN
- Publication Type:Journal Article
- Keywords:
Hydrothorax,hydroperitoneum;
Thermochemotherapy;
T cell subset;
Vascular endothelial growth factor
- From:
Journal of Medical Postgraduates
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the recent effects and toxicity of thermochemotherapy on malignant hydrothorax or hydroperitoneum,to evaluate the changes of the immunological functions,and to investigate the mechanism of thermochemotherapy.Methods:Fifty-two patients were treated with weekly intracavitary chemotherapy,and then combined with local endogenetic thermotherapy twice a week.As the control,another 50 patients received weekly intracavitary chemotherapy.The treatment lasted for two weeks and was followed by one-week rest,and then the recent effects and toxicity were observed.The T cell subset,NK cells and VEGF levels in serum,hydrothorax or hydroperitoneum were tested.Results:Overall response rates of the malignant hydrothorax were 86.9% vs 60.0%(P
