A Case of Extramedullary Hematopoiesis Presenting as a Lung Mass in a Patient with Primary Myelofibrosis.
10.4046/trd.2009.67.3.244
- Author:
Yeo Myeong KIM
1
;
Hyeon Tae KIM
;
Geum Youb NOH
;
Min Soo KANG
;
Yoon Hwan CHANG
;
Hye Ryoun KIM
;
Jae Cheol LEE
;
Cheol Hyeon KIM
Author Information
1. Department of Internal Medicine, Korea Cancer Center Hospital, Korea Institute of Radiological & Medical Sciences, Seoul, Korea. cheol@kcch.re.kr
- Publication Type:Case Report
- Keywords:
Extramedullary hematopoiesis;
Primary myelofibrosis;
Lung mass
- MeSH:
Adipose Tissue;
Aged, 80 and over;
Biopsy;
Bone Marrow;
Hematopoiesis, Extramedullary;
Humans;
Liver;
Lung;
Male;
Megakaryocytes;
Needles;
Primary Myelofibrosis;
Spleen;
Thrombocytopenia
- From:Tuberculosis and Respiratory Diseases
2009;67(3):244-248
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary myelofibrosis is characterized by replacement of bone marrow with fibrotic tissue and the development of extramedullary hematopoiesis. Extramedullary hematopoiesis primarily involves the spleen and liver, but can also occur in the lungs. We report the case of an 80-year-old male who was admitted for evaluation of a lung mass and persistent thrombocytopenia. A percutaneous needle aspiration from the mass in the right lower lung showed myelopoietic cells with fatty tissue. A bone marrow biopsy revealed a hypercellular marrow with an increased number of atypical megakaryocytes. The final diagnosis was a prefibrotic stage of primary myelofibrosis leading to extramedullary hematopoiesis in the lung.
