Effect of low intensity ultrasound on dexamethasone-induced intraocular hypertension in rabbit
- VernacularTitle:低强度超声对激素诱导的兔高眼压的作用
- Author:
Lin CHEN
;
Su LIU
- Publication Type:Journal Article
- Keywords:
animal model;
dexamethasone-induced intraocular hypertension;
ultrasonic therapy
- From:
Basic & Clinical Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of low-intensity ultrasound on intraocular hypertension and its mechanicsm.Methods The intraocular hypertension rabbits were treated with ultrasound.The intraocular pressure(IOP),trabecular meshwork HE staining,EM microscopy,extracellular matrix through immunohistochemistry were performed.Results After treatment,IOP was descended and trabecula interspace was wider than the control eye.The expression of collagen I,laminin and fibronectin was inhibited.Conclusion Low-intensity ultrasound can decrease IOP.It may be related with the change of histologic structure of trabecular meshwork.
