Effects of filling extraction socket with polylactic acid/polyglycolic acid on bone healing in rats
- VernacularTitle:聚乳酸-聚羟基乙酸植入大鼠拔牙创对骨愈合的影响
- Author:
Zhe WU
;
Chang LIU
;
Lei GUO
;
Yuan CHEN
;
Hongchen SUN
- Publication Type:Journal Article
- Keywords:
tooth extraction;
tooth socket;
porous polylactic acid/polyglycolic acid copolymer;
bone remodeling
- From:
Journal of Jilin University(Medicine Edition)
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of porous polylactic acid/polyglycolic acid copolymer(PLGA) filling into extraction socket on the regeneration of alveolar bone in rats.Methods Sixty male Wistar rats were divided into experimental group and control group(n=30).PLGA scaffold was immediately implanted in the mandibular incisor root sockets after removal of incisor teeth.Soft X-ray photography,structural observation,light microscopy were used to evaluate the effects of composite on bone healing in a rat tooth extraction socket.Results The relative lengths of residual alveolar ridge in the experimental group 4,8 weeks after operation were shorter than that in the control group,and there were significant differences between the experimental group and the control group(P
