Association between MTHFRC677T,CBS844ins68 polymorphism and young ischemic stroke
- VernacularTitle:青年缺血性脑卒中与MTHFRC677T、CBS844ins68基因多态性的关系
- Author:
Le FANG
;
Tianwei WANG
;
Yankun SHAO
;
Hong YANG
- Publication Type:Journal Article
- Keywords:
5,10-methylenetetrahydrofolate reductase;
cystathionine beta-synthase;
cerebrovascular acident;
polymorphism(genetics)
- From:
Journal of Jilin University(Medicine Edition)
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the genetic association of MTHFRC677T between CBS844ins68 polymorphism and young ischemic stroke.Methods The polymorphism of MTHFRC677T and CBS844ins68 in 98 stroke patients and 116 control subjects were examined and analyzed by using PCR-RFLP.Results The frequencies of two alleles were as follows: T allele 54.09%,C allele 45.91% in patients and T 37.93%,C 62.07% in controls(?2=11.18,P
