Expression of CD44 gene in non-small cell lung cancer tissue and relationship with prognosis
- VernacularTitle:CD44基因在非小细胞肺癌组织中的表达及其与预后的关系
- Author:
Guanghu LI
;
Yong WU
;
Tong FU
;
Bin ZHANG
;
Guojun LIU
- Publication Type:Journal Article
- Keywords:
CD44;
non-small cell lung cancer;
RT-polymerase chain reaction
- From:
Journal of Jilin University(Medicine Edition)
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of CD44 gene in non-small cell lung cancer(NSCLC) tissue and the relationship with prognosis.Methods The expressions of CD44 gene in 36 specimens from 36 patients with NSCLC were determined by RT-PCR and all the patients were followed up for 3 years.Results CD44 gene was excessively expressed in 21 of 36 specimens of NSCLC tissues,excessive expression rate was 58.3%.The expression of CD44 mRNA in NSCLC tissue was related to metastasis of lymph node(?2 =9.787,P
