Effect of Chinese Herb Sinitang (Monkshood,ginger and licorice) on Blood Pressure in Renovascular Hypertensive Rats
- VernacularTitle:四逆汤(附子、干姜、甘草)对肾血管性高血压大鼠血压调节作用的实验研究
- Author:
Xuewei YANG
;
Yunliang GUO
;
Zhuo CHONG
;
Jun CHEN
;
Fufeng JIAO
- Publication Type:Journal Article
- Keywords:
Sinitang;
Renovascular hypertension;
Ang Ⅱ;
CGRP;
Apoptosis;
Rats
- From:
Chinese Journal of Hypertension
2007;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of a Chinese herbs mixture(Monkshood,ginger and licorice)on blood pressure(BP)and its possible mechanism in renovascular hypertensive rats.Methods 2K1C hypertensive rats received placebo(n=8)or Sinitung(n=8)by gavage for 2 weeks.BP was measured by tail-cuff.Plasma angiotensin Ⅱ(Ang Ⅱ)and calcium gene related peptide(CGRP)were examined by histochemical assay.Results Sinitang treatment significantly decreased BP(116.2?8.3 mm Hg vs placebo:131.6?14.2 mm Hg,P
