ClassⅠ Integron and Its Correlation with Genes Coding for ESBLs in ESBLs-producing Escherichia coli and Klebsiella pneumoniae
- VernacularTitle:产超广谱?-内酰胺酶大肠埃希菌和肺炎克雷伯菌Ⅰ类整合子及其与ESBLs基因关系的研究
- Author:
Yingmei FU
;
Fengmin ZHANG
;
Wenli ZHANG
;
Heguang ZHANG
;
Xiaobei CHEN
;
Weiyuan GUO
;
Jiayu MA
- Publication Type:Journal Article
- Keywords:
Integron;
Antibiotic resistant gene;
Horizontal transfer
- From:
Chinese Journal of Nosocomiology
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To survey the distribution of class Ⅰ integron in extended-spectrum beta-lactamases(ESBLs)-producing Escherichia coli and Klebsiella pneumoniae and its contribution in horizontal transfer of ESBLs genes.METHODS The presence of class Ⅰ integron among 230 ESBLs-producers and 197 non-ESBLs-producers of E.coli and K.pneumoniae were detected by PCR.The correlation and co-transfer between integron and genes coding for SHV,CTX and TEM were studied. RESULTS One hundred and thirty-seven(59.6%) isolates were positive for intⅠ gene among ESBLs-producers,contrasted to 48(24.4%) in non-ESBLs-producers(P
