Antimicrobial Susceptibility and Classification of ?-Lactamases Produced by Kluyvera cryocrescens
- VernacularTitle:栖冷克吕沃尔菌耐药性及?-内酰胺酶检测
- Author:
Desong MING
- Publication Type:Journal Article
- Keywords:
Kluyvera cryocrescens;
?-Lactamases;
Classification;
Susceptibility
- From:
Chinese Journal of Nosocomiology
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the antimicrobial susceptibility,classification and distribution of the ?-lactamases produced by Kluyvera cryocrescens.METHODS To detect the ?-lactamases produced by 17 strains of K.cryocrescens with a multi-disk test [synergy test,and antagonized test for the inducible AmpC ?-lactamases(IABLs)],AmpC ?-lactamases(ABLs)phenotype test and extended-spectrum ?-lactamases(ESBLs) confirment test,and the susceptibility of antimicrobial agents.RESULTS The resistant rate to AMP,GEN,CFZ and SXT was 100.0%,88.2%,88.2% and 88.2%,respectively,and that to IMP,CIP and AMK was 0.0%,35.3%,and 47.1%,respectively;all of 17 strains produced the ?-lactamases(100.0%),two strains produced penicillinases(11.8%),six strains produced broad-spectrum ?-lactamases(35.3%) and nine strains produced ESBLs(52.9%),1 strain produced ABLs,and 1 strain produced ESBLs+high product ABLs,all did not produce carbapenem-hydrolyzing ?-lactamases(CHBLs).CONCLUSIONS The resistant rate of K.cryocrescens is very high,all multi-resistant.The resistant rate of K.cryocrescens to AMP,GEN,CFZ and SXT is high,but to IMP,CIP and AMK is lower.The rate of ?-lactamases produced by the 17 strains of K.cryocrescens is very high,four classes of ?-lactamases are produced by five types,mainly BSBLs and ESBLs,without CHBLs.
