Study on the relationship between complement activation and inflammatory reaction in tissues of the perihematoma in patients with intracerebral hemorrhage
- VernacularTitle:脑出血患者血肿周围组织补体激活与炎性反应的相关性研究
- Author:
Fuqiang GUO
;
Xiaojia LI
;
Longyi CHEN
- Publication Type:Journal Article
- Keywords:
intracerebral hemorrhage;
perihematoma;
complement;
inflammatory reaction
- From:
Journal of Clinical Neurology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
72 h goups, respectively. A few tissues distant from the hematoma on the way into the cranium were taken from the 2 former groups as control. Immunohistochemistry staining and reverse transcription polymerase chain reaction (RT-PCR) were used to detected expression of complement facters C3 ,complement inhibitor (Clusterin),the infiltration of the inflammatory cells, the proliferation of neuroglia cells and the expression of cytokins.Results The immunohistochemistry staining showed that the expression of complement facter C3 got to the peak at 12~72 h (P
