Clinical effect of Exelon and the high pressure oxygen uniting to treat the elderly dementia and influence of Exelon on plasma TGF-?,IGF-1 and ICAM-1 in patients with elderly dementia
- VernacularTitle:艾斯能和高压氧治疗老年期痴呆的临床疗效及艾斯能对患者血浆TGF-?、IGF-1及ICAM-1的影响
- Author:
Guoping TIAN
;
Bing XU
;
Lihua WU
- Publication Type:Journal Article
- Keywords:
Exelon;
the high pressure oxygen;
elderly dementia;
TGF-?;
IGF-1;
ICAM-1
- From:
Journal of Clinical Neurology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of Exelon and the high pressure oxygen uniting to treat the old-age period of dementia and influence of Exelon on plasma transforming growth factor ?(TGF-?), insulin-like growth factor 1(IGF-1)and intercellular adhesion molecule-1(ICAM-1) in patients with elderly dementia.Methods 172 cases with ?lzheimer's diseases (AD) and 202 cases with vascular dementia (VD) were randomly divided into Exelon group, high pressure oxygen group, uniting group (taking Exelon and doing the high pressure oxygen together) and piracetam group. The MMSE scores were graded before and after treatment. TGF-?, IGF-1 and ICAM-1 were detected in Exelon group before and after treatment.Results MMSE scores had improved in Exelon group, high pressure oxygen group and uniting group after the treatment in AD group and VD group (all P
