Progress in activator protein-1 and the allergic diseases
- VernacularTitle:激活蛋白-1与变应性疾病的研究进展
- Author:
Yamin ZHANG
;
Lisi LIU
- Publication Type:Journal Article
- Keywords:
Activator Protein-1;
Allergic diseases;
Gene transcriptional regulation;
Cellular signal transduction
- From:
Journal of Medical Postgraduates
2004;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Activator protein-1(AP-1) is a collective term referring to dimeric transcription factors composed of Jun protein family and Fos protein family that bind to the AP-1 sites of many genes,also known as TPA-responsive elements.AP-1 involves in the gene transcriptional regulation of a large number of growth factors and cytokines and leads to a series of physiological and pathophysiological changes of the body.Increasing attention has been paid to the relationship between AP-1 and the allergic diseases in recent years.This article reviewed the structure?activation of AP-1,and the relationship between AP-1 and the allergic diseases.
