Serum HBV-DNA Level in HBsAg Positive Patients Before and after Operation and Their Infectious Risk in Hospital
- VernacularTitle:HBsAg阳性患者手术期间HBV-DNA的变化及其传染性分析
- Author:
Jianfang HE
;
Cuifen SHEN
;
Fuchu QIAN
;
Ning ZHAO
;
Licheng DAI
;
Jinhua GU
;
Qiang YAN
- Publication Type:Journal Article
- Keywords:
HBsAg;
Surgical patient;
HBVDNA;
Surgical intervention;
Drainage
- From:
Chinese Journal of Nosocomiology
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the changes in serum HBV-DNA level in HBsAg positive patients before and after operation and their infectious risk in hospital.METHODS HBV markers(HBV-M) in serum was detected in 58 HBsAg positive patients by time-resolved fluoroimmunometric assay before operation.HBV-DNA level in serum of them before operation and at 3rd,and 7th day after operation was detected by real time fluorescent quantitative polymerase chain reaction.We also detected HBV-DNA in gastric drainage juice and abdominal drainage after operation.RESULTS HBV-DNA was detected in 27 of 58 HBsAg positive patients' serum,the positive rate was 46.1%.After operation,serum HBV-DNA was increased remarkably at 3rd and 7th day compared with before operation in these patients respectively(P
