Combination Antimicrobial Susceptibility Test on 43 Multi-drug-resistant Isolates of Pseudomonas aeruginosa
- VernacularTitle:多重耐药铜绿假单胞菌体外联合药敏研究
- Author:
Yaping XU
;
Jingrong CAO
;
Lianzan LI
;
Ling TANG
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
Minimal inhibitory concentration(MIC);
Fractional inhibitory concentration(FIC);
Antibiotics
- From:
Chinese Journal of Nosocomiology
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the combined effect of cefoperazone/sulbactam with levofloxacin(group 1) and polymyxin B with rifampin(group 2) on 43 isolates of multi-drug-resistant Pseudomonas aeruginosa. METHODS The minimal inhibitory concentration(MIC) of all the antibiotics mentioned above was determined by agar dilution method.Fractional inhibitory concentration(FIC) index was calculated for all the selected isolates with all combinations,and the activities of antibiotics alone and in combination against the selected strains were evaluated. RESULTS The MIC of all the combined antimicrobials was reduced significantly(P
